CRTC1 Polyclonal Antibody
Produktgrößen
60 ul
£319,00
RD88192A-60UL
120 ul
£479,00
RD88192A-120UL
200 ul
£761,00
RD88192A-200UL
Über dieses Produkt
- SKU:
- RD88192A
- Zusätzliche Namen:
- CRTC1,MECT1,TORC-1,TORC1,WAMTP1
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This is a CRTC1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CRTC1
- Isotyp:
- IgG
- Molekulargewicht:
- 80-85kDa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:crtc1-polyclonal-antibody-31440.html