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Antikörper

CDK12 Polyclonal Antibody

Produktgrößen
60 ul
£319,00
RD88038A-60UL
120 ul
£479,00
RD88038A-120UL
200 ul
£761,00
RD88038A-200UL
Über dieses Produkt
SKU:
RD88038A
Zusätzliche Namen:
CDK12,CRK7,CRKR,CRKRS
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD of the large subunit of RNA polymerase II (POLR2A, thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.|This is a CDK12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human CDK12
Isotyp:
IgG
Molekulargewicht:
53kda
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody