NCF4 Polyclonal Antibody
Produktgrößen
60 ul
£319,00
RD86809A-60UL
120 ul
£479,00
RD86809A-120UL
200 ul
£761,00
RD86809A-200UL
Über dieses Produkt
- SKU:
- RD86809A
- Zusätzliche Namen:
- NCF4,CGD3,NCF,P40PHOX,SH3PXD4
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.|This is a NCF4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human NCF4
- Isotyp:
- IgG
- Molekulargewicht:
- 48KDa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:ncf4-polyclonal-antibody-30348.html