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Antikörper

NF2 / Merlin Polyclonal Antibody

Produktgrößen
50 ul
£218,00
RD86690A-50UL
100 ul
£359,00
RD86690A-100UL
Über dieses Produkt
SKU:
RD86690A
Zusätzliche Namen:
ACN,BANF,Merlin,Neurofibromin 2,neurofibromin 2 (merlin),NF2,SCH,Schwannomerlin,Schwannomin
Anwendung:
Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
2.2 mg/ml
Weitere Details:
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway,a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.|This is a NF2 / Merlin Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant Human NF2 protein expressed by E.coli.
Isotyp:
IgG
Molekulargewicht:
13kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody