IRAK1BP1 Polyclonal Antibody
Produktgrößen
20 ul
£148,00
RD75236A-20UL
60 ul
£242,00
RD75236A-60UL
120 ul
£372,00
RD75236A-120UL
200 ul
£585,00
RD75236A-200UL
Über dieses Produkt
- SKU:
- RD75236A
- Zusätzliche Namen:
- ActA binding protein 3,AIP70,Interleukin 1 receptor associated kinase 1 binding protein 1,IRAK1-binding protein 1,Signaling molecule that associates with Pelle-like kinase,SIMPL
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.4 mg/ml
- Weitere Details:
- SIMPL, also known as IRAK1BP1 (interleukin-1 receptor-associated kinase 1-binding protein 1), is a 260 amino acid protein belonging to the IRAK1BP1 family. In addition to containing an intrinsically disordered region which associates with HSPA1 and HSPA8, SIMPL also interacts directly with IRAK1 and promotes RELA transcriptional activity. SIMPL is a major component of the IRAK1-dependent TNFRSF1A signaling pathway in which TNF-alpha induces NF-kappa-B gene transcription, leading to an inhibition of proinflammatory cytokines. Inactivation of SIMPL inhibits tumor necrosis factor receptor type I-induced NF-kappaB activity. Localizing to the nucleus and cytoplasm, SIMPL requires the phosphorylation of Ser-56 and/or Ser-62 to be fully active.|This is a IRAK1BP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human IRAK1BP1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:irak1bp1-polyclonal-antibody-8620.html