JUN Polyclonal Antibody
Produktgrößen
60 ul
£265,00
RD70562A-60UL
120 ul
£399,00
RD70562A-120UL
200 ul
£600,00
RD70562A-200UL
Über dieses Produkt
- SKU:
- RD70562A
- Zusätzliche Namen:
- Activator protein 1,AP 1,AP1,cJun,Enhancer Binding Protein AP1,Jun Activation Domain Binding Protein,JUN,Jun oncogene,JUN protein,Jun proto oncogene,JUN,JUNC,Oncogene JUN,p39,Proto oncogene c jun,Proto oncogene cJun,Proto-oncogene c-jun,Transcription Fact
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1.1 mg/ml
- Weitere Details:
- JUN is also named as c-Jun and AP1,belongs to the bZIP family and Jun subfamily. JUN,the most extensively studied protein of the activator protein-1 (AP-1) complex,is involved in numerous cell activities,such as proliferation,apoptosis,survival,tumorigenesis and tissue morphogenesis. JUN is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. JUN is a basic leucine zipper (bZIP) transcription factor that acts as homo- or heterodimer,binding to DNA and regulating gene transcription. In additon,extracellular signals can induce post-translational modifications of JUN,resulting in altered transcriptional activity and target gene expression. More over,it has uncovered multiple layers of a complex regulatory scheme in which JUN is able to crosstalk,amplify and integrate different signals for tissue development and disease. Jun is predominantly nuclear,ubiquitinated Jun colocalizes with lysosomal proteins.|This is a JUN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Human c-Jun.
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:jun-polyclonal-antibody-8335.html