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Antikörper

BRCA2 Polyclonal Antibody

Produktgrößen
20 ul
£138,00
RD70171A-20UL
60 ul
£218,00
RD70171A-60UL
120 ul
£359,00
RD70171A-120UL
200 ul
£560,00
RD70171A-200UL
Über dieses Produkt
SKU:
RD70171A
Zusätzliche Namen:
BRCA 2, BRCC 2, Breast and ovarian cancer susceptibility gene early onset antibody, BROVCA2, FACD, FAD 1, FANCB, GLM3
Anwendung:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.|This is a BRCA2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant Human Breast cancer type 2 susceptibility protein
Isotyp:
IgG
Molekulargewicht:
384 kDa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody