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Antikörper

APC Anti-Human CD279/PD-1 Antibody

Produktgrößen
20 tests
£187,00
RD30417F-20TESTS
100 tests
£324,00
RD30417F-100TESTS
2 x 100 tests
£469,00
RD30417F-2X100TESTS
Über dieses Produkt
SKU:
RD30417F
Zusätzliche Namen:
PDCD1,PD1,Protein PD-1,hPD-1
Anwendung:
Flow Cytometry
Buffer:
PBS
Klonalität:
Monoclonal
Konjugat:
APC
Weitere Details:
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.|This is a APC Anti-Human CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Isotyp:
IgG1, kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Reddot
Typ:
Antibody: Monoclonal Antibody