AF/LE Purified Anti-Human CD279/PD-1 Antibody
Produktgrößen
50 ug
£178,00
RD30295F-50UG
500 ug
£580,00
RD30295F-500UG
1 mg
£848,00
RD30295F-1MG
Über dieses Produkt
- SKU:
- RD30295F
- Zusätzliche Namen:
- PD-1, Programmed Death-1
- Anwendung:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- Klonalität:
- Monoclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.|This is a AF/LE Purified Anti-Human CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:af-le-purified-anti-human-cd279-pd-1-antibody-7446.html