NUAK1 Polyclonal Antibody
Produktgrößen
60 ul
£319,00
RD267108A-60UL
120 ul
£479,00
RD267108A-120UL
200 ul
£761,00
RD267108A-200UL
Über dieses Produkt
- SKU:
- RD267108A
- Zusätzliche Namen:
- NUAK1,ARK5
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.|This is a NUAK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human NUAK1 (NP_055655.1).
- Isotyp:
- IgG
- Molekulargewicht:
- 74 kDa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Reddot
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:nuak1-polyclonal-antibody-6360.html