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Antikörper

CCNE1 Polyclonal Antibody

Produktgrößen
20 ul
£148,00
RD219281A-20UL
60 ul
£242,00
RD219281A-60UL
120 ul
£372,00
RD219281A-120UL
200 ul
£585,00
RD219281A-200UL
Über dieses Produkt
SKU:
RD219281A
Zusätzliche Namen:
CCNE,Ccne1,CCNE1,cyclin E variant ex5del,cyclin E variant ex7del,Cyclin E1,Cyclin Es,Cyclin Et,CyclinE,G1/S specific cyclin E,G1/S-specific cyclin-E1
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.9 mg/ml
Weitere Details:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.|This is a CCNE1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CCNE1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody