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Antikörper

CRACR2A Polyclonal Antibody

Produktgrößen
20 ul
£148,00
RD219269A-20UL
60 ul
£242,00
RD219269A-60UL
120 ul
£372,00
RD219269A-120UL
200 ul
£585,00
RD219269A-200UL
Über dieses Produkt
SKU:
RD219269A
Zusätzliche Namen:
Calcium release-activated calcium channel regulator 2A,CRAC channel regulator 2A,CRACR2A,EF hand calcium binding domain 4B,EF hand calcium binding domain containing protein 4B,EF-hand calcium-binding domain-containing protein 4B,EFC4B,EFCAB 4B,Efcab4b,FLJ
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.84 mg/ml
Weitere Details:
Ca2+-binding protein that plays a key role in store-operated Ca2+entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.|This is a CRACR2A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Fusion protein of human CRACR2A
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody