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Antikörper

NARF Polyclonal Antibody

Produktgrößen
20 ul
£148,00
RD218713A-20UL
60 ul
£242,00
RD218713A-60UL
120 ul
£372,00
RD218713A-120UL
200 ul
£585,00
RD218713A-200UL
Über dieses Produkt
SKU:
RD218713A
Zusätzliche Namen:
DKFZp434G0420,FLJ10067,GC17P078009,IOP2,Iron only hydrogenase like protein 2,Nuclear prelamin A recognition factor,Prenyl dependent prelamin A binding protein
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
1.56 mg/ml
Weitere Details:
Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.|This is a NARF Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Fusion protein of human NARF
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody