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Antikörper

IMPA1 Polyclonal Antibody

Produktgrößen
20 ul
£148,00
RD218668A-20UL
60 ul
£242,00
RD218668A-60UL
120 ul
£372,00
RD218668A-120UL
200 ul
£585,00
RD218668A-200UL
Über dieses Produkt
SKU:
RD218668A
Zusätzliche Namen:
IMP 1,IMP,IMPA 1,IMPA,IMPA1,IMPA1,IMPase 1,IMPase,Inositol 1(or 4) monophosphatase,Inositol monophosphatase 1,Inositol monophosphatase,Inositol(myo) 1(or 4) monophosphatase 1,Inositol-1(or 4)-monophosphatase 1,Lithium sensitive myo inositol monophosphatas
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Konzentration:
0.9 mg/ml
Weitere Details:
This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.|This is a IMPA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Fusion protein of human IMPA1
Isotyp:
IgG
Molekulargewicht:
Refer to figures
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Reddot
Typ:
Antibody: Polyclonal Antibody