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Antikörper

AF488 Anti-Human CD49d Antibody

Produktgrößen
20 tests
£211,00
RD21766F-20TESTS
100 tests
£433,00
RD21766F-100TESTS
2 x 100 tests
£620,00
RD21766F-2X100TESTS
Über dieses Produkt
SKU:
RD21766F
Zusätzliche Namen:
Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha,CD49d,ITGA4
Anwendung:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
9F10
Klonalität:
Monoclonal
Konjugat:
Alexa Fluor® 488
Weitere Details:
CD49d is a 150 kD A Alpha integrin chain known as A Alpha4 integrin or VLA-4 A Alpha chain. It forms a heterodimer with either integrin B Beta1 (A Alpha4B Beta1, VLA-4) or B Beta7 (A Alpha4B Beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. A Alpha4B Beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.|This is a AF488 Anti-Human CD49d Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Isotyp:
IgG1, kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Reddot
Typ:
Antibody: Monoclonal Antibody