APC Anti-Mouse CD206 Antibody
Produktgrößen
50 tests
£171,00
RD21673F-50TESTS
100 tests
£211,00
RD21673F-100TESTS
2 x 100 tests
£305,00
RD21673F-2X100TESTS
Über dieses Produkt
- SKU:
- RD21673F
- Zusätzliche Namen:
- MMR,MR,MRC1,macrophage mannose receptor,mannose receptor
- Anwendung:
- Flow Cytometry, Immunocytochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- C068C2
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.|This is a APC Anti-Mouse CD206 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rat
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:apc-anti-mouse-cd206-antibody-1377.html