AF/LE Purified Anti-Human CD274/PD-L1 Antibody
Produktgrößen
50 ug
£178,00
RD21663F-50UG
500 ug
£580,00
RD21663F-500UG
1 mg
£848,00
RD21663F-1MG
Über dieses Produkt
- SKU:
- RD21663F
- Zusätzliche Namen:
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
- Anwendung:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- 0.2 uM PBS
- translate.label.attr.clone:
- 29E.2A3
- Klonalität:
- Monoclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.|This is a AF/LE Purified Anti-Human CD274/PD-L1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotyp:
- IgG2b, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Reddot
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:af-le-purified-anti-human-cd274-pd-l1-antibody-1367.html