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Antikörper

AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody

Produktgrößen
50 ug
£151,00
RD21654F-50UG
500 ug
£379,00
RD21654F-500UG
1 mg
£647,00
RD21654F-1MG
Über dieses Produkt
SKU:
RD21654F
Zusätzliche Namen:
B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
0.2 uM PBS
translate.label.attr.clone:
10F.9G2
Klonalität:
Monoclonal
Konzentration:
0.5 mg/ml
Weitere Details:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-G Gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-G Gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.|This is a AF/LE Purified Anti-Mouse CD274/PD-L1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rat
Isotyp:
IgG2b, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Reddot
Typ:
Antibody: Monoclonal Antibody