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Antikörper

AF/LE Purified Anti-Mouse CD22 Antibody

Produktgrößen
50 ug
£151,00
RD20362F-50UG
500 ug
£379,00
RD20362F-500UG
1 mg
£647,00
RD20362F-1MG
Über dieses Produkt
SKU:
RD20362F
Zusätzliche Namen:
B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2
Anwendung:
Flow Cytometry
Buffer:
0.2 uM PBS
translate.label.attr.clone:
Cy34.1
Klonalität:
Monoclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig u chain are augmented in the presence of Cy34.1 mAb.|This is a AF/LE Purified Anti-Mouse CD22 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Isotyp:
IgG1, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Reddot
Typ:
Antibody: Monoclonal Antibody