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Antikörper

anti-Drebrin, guinea pig polyclonal antibody

Produktgrößen
100 ul
£354,00
GP254-100UL
Über dieses Produkt
SKU:
GP254
Zusätzliche Namen:
Drebrin, Developmentally-regulated brain protein, DBN1, D0S117E
Anwendung:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
CE/IVD:
RUO
Klonalität:
Polyclonal
Weitere Details:
The antiserum specifically reacts with drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000). Drebrin has originally been described only in neuronal cells, but has been recently found also in the actin-rich lamellipodia and filopodia of motile cells. It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues, including diverse epithelia and carcinoma (e.g. in epidermis basal cells are positive, whereas overlying cells are negative; also positive: regenerating epithelium during wound healing; basal cell carcinoma; skin melanoma), specific types of endothelia and smooth muscle; especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis. Also positive: epithelia of hair follicles and eccrine sweat glands. Consistently negative were, however, hepatocytes and cross-striated muscle. Positive cultured cell lines: PLC, U333, HUVEC, HaCat, HeLa, MCF-7, SV-80, B1; B16 (mouse melanoma cells)
Formulierung:
Contains 0.09% sodium azide
Host:
Guinea Pig
Immunogen:
Synthetic human peptide (aa 254-272) coupled to KLH
Aufreinigung:
Stabilized antiserum
Reaktivitäten:
Bovine, Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Please refer to datasheet
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:GP254