anti-MALT1, EBS-T-007, mouse monoclonal antibody
Produktgrößen
100 ug
£432,00
691674-100UG
Über dieses Produkt
- SKU:
- 691674
- Zusätzliche Namen:
- Mucosa-associated lymphoid tissue lymphoma translocation protein 1, EC 3.4.22.-, MALT lymphoma-associated translocation, Paracaspase, MALT1, MLT
- Anwendung:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-T-007
- Klonalität:
- Monoclonal
- Konzentration:
- 100 ug/ml
- Weitere Details:
- EBS-T-007 reacts with paracaspase MALT1, crucial for B- and T-cell activation/proliferation and activation of transcription factor NF-kappaB. It has a N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (BCL10) protein and a caspase-like domain. MALT1 and BCL10 can both be found translocated in MALT lymphoma. In such cases either BCL10 or MALT1 or both are highly expressed, depending on the site of translocation. Normal cells and MALT lymphomas lacking translocations exhibit much lower levels of expression. Positive control: HepG2 cells or lymphoma.
- Formulierung:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Human MALT1 recombinant protein
- Isotyp:
- IgG1, kappa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:691674
