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Antikörper

anti-MHC-II-DRA, EBS-O-111, mouse monoclonal antibody

Produktgrößen
100 ug
£432,00
691664-100UG
Über dieses Produkt
SKU:
691664
Zusätzliche Namen:
HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA, HLA-DRA, HLA-DRA1
Anwendung:
FACS, Immunohistochemistry
CE/IVD:
RUO
translate.label.attr.clone:
EBS-O-111
Klonalität:
Monoclonal
Konzentration:
100 ug/ml
Weitere Details:
MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an alpha and beta chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B-cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. Positive control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
Formulierung:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
RAJI cells
Isotyp:
IgG2a, kappa
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Please refer to datasheet
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:691664