anti-HSP27, EBS-O-060, mouse monoclonal antibody
Produktgrößen
100 ug
£432,00
691661-100UG
Über dieses Produkt
- SKU:
- 691661
- Zusätzliche Namen:
- Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27, HSPB1, HSP27, HSP28
- Anwendung:
- ELISA, FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-O-060
- Klonalität:
- Monoclonal
- Konzentration:
- 100 ug/ml
- Weitere Details:
- EBS-O-060 reacts with heat shock protein 27 (HSP27) in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian alpha-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors. Positive control: ~50% of breast cancers are positive for HSP27, especially those that are also positive for ER and/or PgR.
- Formulierung:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- HSP27 derived from MCF-7
- Isotyp:
- IgG1, kappa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Avian, Human, Mouse, Non-human Primate, Rat, Sheep
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:691661
