anti-CD11a, 87-6F9, mouse monoclonal antibody
Produktgrößen
100 ug
£432,00
691559-100UG
Über dieses Produkt
- SKU:
- 691559
- Zusätzliche Namen:
- Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD antigen CD11a, ITGAL, CD11A
- Anwendung:
- FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 87-6F9
- Klonalität:
- Monoclonal
- Konzentration:
- 100 ug/ml
- Weitere Details:
- 87-6F9 reacts with CD11a, a transmembrane molecule with 1,145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells tend to increase. CD11a plays a key role in mediating leucocyte adhesion to endothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 adhesion. 87-6F9 potently blocks LFA-1 dependent homotypic cell aggregation and was typed in the IVth International Leucocyte Typing Workshop. Positive control: human leucocytes.
- Formulierung:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Stimulated human leucocytes
- Isotyp:
- IgG2b, kappa
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:691559
