anti-Cyclin D1, DCS-6, mouse monoclonal antibody
Produktgrößen
20 ug
£122,00
690053-20UG
100 ug
£275,00
690053-100UG
Über dieses Produkt
- SKU:
- 690053
- Zusätzliche Namen:
- G1/S-specific cyclin-D1, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, PRAD1 oncogene, CCND1, BCL1, PRAD1
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- DCS-6
- Klonalität:
- Monoclonal
- Konzentration:
- 100 ug/ml
- Weitere Details:
- DCS-6 reacts specifically with cyclin D1 protein present predominantly in G1 phase of cell cycle; it does not cross-react with D2 or D3 cyclins (the closest relatives within the cyclin family); DCS-6 is especially useful in tumor diagnosis: it can be used as fast method to identify cases with 11q13 amplifications. Cyclin D1 gene is identical to the BCL-1 and the PRAD-1 oncogene and is part of the chromosome 11q13 amplicon which is amplified in several common tumor types like breast, lung, esophagus, urinary bladder and head and neck carcinoma. Polypeptide reacting: Mr 36 kDa polypeptide (cyclin D1 polypeptide of human cells). Reactivity on cultured cell lines: MCF-7, MDA-MB-134 and MDA-MB-231 (breast cancer cell lines), UMSC22 (squamous cell carcinoma cell line), U-2-OS (osteosarcoma cell line), RT-112, A431, HT-29, 3T3-L1, Ins-1. The expression of Cyclin D1 is tissue specific and associated with tumor onset and progression.
- Formulierung:
- 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4
- Host:
- Mouse
- Immunogen:
- Human recombinant full-length cyclin D1 protein
- Isotyp:
- IgG2a
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Canine, Human, Mouse, Non-human Primate, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:690053







