anti-Keratin Type II, AE3, mouse monoclonal antibody
Produktgrößen
200 ug
£308,00
61806-200UG
Über dieses Produkt
- SKU:
- 61806
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- AE3
- Klonalität:
- Monoclonal
- Konzentration:
- 200 ug/ml
- Weitere Details:
- AE 3 represents an excellent marker for distinguishing carcinoma from non-epithelial tumors. Tumors specifically detected: all epithelia and their neoplasms. Polypeptide reacting: Mr 53,000 to Mr 67,000 basic type II keratin polypeptides of human epithelial proteins (keratins - formerly also designated cytokeratins - nos. K1 - K8). Epitope has been mapped to aa 266-299 on alpha-helical rod domain (see Waseem et al., 2004). Reactivity on cultured cell lines: MCF-7, A-431, RT 112. Waseem A, Karsten U, Leigh IM, Purkis P, Waseem NH, Lane BE: Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. Biochemistry 43, 1283-1295 (2004)
- Formulierung:
- PBS pH 7.4 with 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- Human epidermal keratin
- Isotyp:
- IgG1
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Avian, Bovine, Human, Mouse, Non-human Primate, Rabbit, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:61806