anti-p97 ATPase, 58.13.3, mouse monoclonal antibody
Produktgrößen
50 ug
£262,00
61078-50UG
Über dieses Produkt
- SKU:
- 61078
- Zusätzliche Namen:
- Transitional endoplasmic reticulum ATPase, TER ATPase, EC 3.6.4.6, 15S Mg(2+-ATPase p97 subunit, Valosin-containing protein, VCP, VCP
- Anwendung:
- Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 58.13.3
- Klonalität:
- Monoclonal
- Konzentration:
- 50 ug/ml
- Weitere Details:
- p97 ATPase/VCP (also described as valosin-containing protein) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with the p97 subunit of 15S Mg2+-ATPase. p97/VCP is involved in ubiquitin-proteasome dependent protein degradation processes and involvement was also found e.g. in the formation of neuronal inclusion bodies in neuro-degenerative diseseases (e.g. Parkinson's disease). Positive control: immunoblots with protein extracts from all vertebrate tissues and cells. Reactivity on cultured cell lines: all vertebrate cells and tissues tested so far: e.g. Xenopus laevis; rabbit, rat, human; does not crossreact with the corresponding protein in budding yeast (Cdc48p).
- Formulierung:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
- Host:
- Mouse
- Immunogen:
- 15S Mg2+ ATPase complex purified from Xenopus laevis ovary
- Isotyp:
- IgG1
- Physischer Zustand:
- Lyophilized
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Amphibian, Human, Rabbit, Rat, Yeast/Fungi
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:61078