anti-LRP, 5A6, mouse monoclonal antibody
Produktgrößen
50 ug
£315,00
61066-50UG
Über dieses Produkt
- SKU:
- 61066
- Anwendung:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 5A6
- Klonalität:
- Monoclonal
- Konzentration:
- 50 ug/ml
- Weitere Details:
- 5A6 specifically reacts with the 85 kDa b-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91). Neutralizing effects of 5A6 have also been reported (Basu et al., 2001). Basu S, Binder RJ, Ramalingam T, Srivastave PK: CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp 70, and calreticulin. Immunity 14, 303-313 (2001)
- Formulierung:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
- Host:
- Mouse
- Immunogen:
- Human LRP/alpha2MR
- Isotyp:
- IgG2b
- Physischer Zustand:
- Lyophilized
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Hamster, Human, Mouse, Rabbit, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:61066