anti-CD44, DF1485, mouse monoclonal antibody
Produktgrößen
1 ml
£251,00
16080-1ML
Über dieses Produkt
- SKU:
- 16080
- Anwendung:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- DF1485
- Klonalität:
- Monoclonal
- Weitere Details:
- CD44 (HCAM) is a transmembrane protein expressed by lymphocytes, erythrocytes and several normal epithelial cells and is a member of the CAM family. It is involved in lymphocyte homing, T-lymphocyte activation, interaction with hyaluronic acid and may act as an adhesion molecule. The human CD44 is composed of 19 exons, 9 variably expressed due to alternative splicing of mRNA; standard CD44 (CD44s) is composed of exons 1-5 and 15-19. The loss of CD44s expression predicts unfavorable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinoma and neuroblastomas. In immunoblotting the antibody reacts with a glycoprotein isolated from hematopoetic cells and epithelial cells with a respective molecular weight of 29-37 kD and 51 kD. Positive control: Tonsil (cell membrane staining).
- Formulierung:
- Contains 0.09% sodium azide
- Host:
- Mouse
- Immunogen:
- CD44 antigen (PGp-1) purified from lymphocyte membrane
- Isotyp:
- IgG1
- Aufreinigung:
- Hybridoma cell culture supernatant
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:16080