8α,9α-Epoxycoleon-U-quinone
Produktgrößen
8α,9α-Epoxycoleon-U-quinone
£ POA
HY-N10564
Über dieses Produkt
- SKU:
- HY-N10564
- CAS Number:
- 93800-59-0
- Weitere Details:
- 8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX[1].
- Molekulargewicht:
- 360.4
- Referenzen:
- [1]Ntungwe EN, et al. C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators. ACS Med Chem Lett. 2022 Mar 11;13(4):674-680.
- Forschungsgebiet:
- Cancer
- Versandbedingungen:
- Ambient