DNA-PK-IN-13
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DNA-PK-IN-13
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HY-158166
Über dieses Produkt
- SKU:
- HY-158166
- CAS Number:
- 3036751-03-5
- Weitere Details:
- DNA-PK-IN-13 (Compound SK10) is a DNA-PK inhibitor that exhibits potent inhibitory activity (IC50= 0.11 nM). DNA-PK-IN-13 regulates tumor cell proliferation by decreasing the expression level of γH2A.X and enhancing the sensitivity of tumor cells to chemotherapeutic agents. DNA-PK-IN-13 is suitable for oncology studies[1].
- Molekulargewicht:
- 414.46
- Referenzen:
- [1]Cheng B, Y et al. Discovery of Novel Heterotricyclic Compounds as DNA-Dependent Protein Kinase (DNA-PK) Inhibitors with Enhanced Chemosensitivity, Oral Bioavailability, and the Ability to Potentiate Cancer Immunotherapy. J Med Chem. 2024 Apr 25;67(8):6253-6267
- Forschungsgebiet:
- Cancer; Inflammation/Immunology
- Versandbedingungen:
- Ambient