5′-Azido-2′;5′-dideoxy-2′-fluorouridine
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HY-154305-1EACH
Über dieses Produkt
- SKU:
- HY-154305
- Anwendung:
- Antibody Microarray
- CAS Number:
- 1012080-88-4
- Weitere Details:
- 5′-Azido-2′;5′-dideoxy-2′-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 5′-Azido-2′;5′-dideoxy-2′-fluorouridine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molekulargewicht:
- 271.21
- Referenzen:
- [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
- Forschungsgebiet:
- Cancer
- Versandbedingungen:
- Ambient
- Typ:
- Molecular Biology Reagents: Nucleic Acids