6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine
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HY-152663-1EACH
Über dieses Produkt
- SKU:
- HY-152663
- Anwendung:
- Antibody Microarray
- Weitere Details:
- 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is a click chemistry reagent; it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Molekulargewicht:
- 306.27
- Referenzen:
- [1]Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107.|[2]Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50.|[3]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
- Forschungsgebiet:
- Cancer
- Versandbedingungen:
- Ambient
- Typ:
- Molecular Biology Reagents: Nucleic Acids