5'-ODMT cEt G Phosphoramidite (Amidite)
Produktgrößen
100 mg
£ POA
HY-148504-100MG
250 mg
£ POA
HY-148504-250MG
Über dieses Produkt
- SKU:
- HY-148504
- CAS Number:
- 945628-66-0
- Weitere Details:
- 5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].
- Molekulargewicht:
- 881.95
- Reinheit:
- 99.88
- Referenzen:
- [1]Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839.|[2]Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81.|[3]Vasquez G, et al., Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839.
- Forschungsgebiet:
- Cardiovascular Disease
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C (Powder; stored under nitrogen; away from moisture)
- Typ:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Cell Cycle/DNA Damage