Eprodisate (Standard)
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Eprodisate (Standard)
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HY-128849R
Über dieses Produkt
- SKU:
- HY-128849R
- CAS Number:
- 21668-77-9
- Weitere Details:
- Eprodisate (Standard) is the analytical standard of Eprodisate. This product is intended for research and analytical applications. Eprodisate is an amyloid inhibitor that interferes with the interaction between amyloidogenic proteins and glycosaminoglycans, thereby inhibiting the aggregation of amyloid fibrils and the deposition of fibrils in tissues. Eprodisate slows the progression of renal disease associated with AA amyloidosis and may be useful for other types of amyloidosis[1][2][3].
- Molekulargewicht:
- 204.22
- Referenzen:
- [1]Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60.|[2]Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? Expert Opin Pharmacother. 2008 Aug;9(12):2175-80.|[3]Quaranta DV, et al. Transport of the Proinflammatory Chemokines C-C Motif Chemokine Ligand 2 (MCP-1) and C-C Motif Chemokine Ligand 5 (RANTES) across the Intact Mouse Blood-Brain Barrier Is Inhibited by Heparin and Eprodisate and Increased with Systemic Inflammation. J Pharmacol Exp Ther. 2023 Jan;384(1):205-223.
- Forschungsgebiet:
- Inflammation/Immunology
- Versandbedingungen:
- Ambient