Human NEDD8 Protein (Recombinant His)
Produktgrößen
100 ug
£ POA
LS-G3502-100UG
20 ug
£ POA
LS-G3502-20UG
500 ug
£ POA
LS-G3502-500UG
Über dieses Produkt
- SKU:
- LS-G3502
- Zusätzliche Namen:
- NEDD8, NEDD-8, Neddylin, Ubiquitin-like protein Nedd8
- Buffer:
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.5mM DTT, 50mM NaCl, 10% glycerol.
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- NEDD8 belongs to the ubiquitin family and human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The NEDD8 system is essential for the regulation of protein degradation pathways involved in cell cycle progression, morphogenesis and tumorigenesis. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Recombinant human NEDD8 protein was expressed in E.coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.
- Reinheit:
- >95%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- LifeSpan Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:3502