Human HBEGF / HB EGF Protein (Recombinant)
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1 unit
£ POA
LS-G27105-1UNIT
25 units
£ POA
LS-G27105-25UNITS
5 units
£ POA
LS-G27105-5UNITS
Über dieses Produkt
- SKU:
- LS-G27105
- Zusätzliche Namen:
- HBEGF, Dtr, DTS, DTSF, HEGFL, Diphtheria Toxin Receptor
- Buffer:
- Lyophilized from PBS
- Weitere Details:
- Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.
- Molekulargewicht:
- 12-14 kDa (SDS-PAGE)
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >95%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C reconstituted., -20[o]C reconstituted. Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- LifeSpan Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:27105