Human GDF15 Protein (Recombinant)
Produktgrößen
20 ug
£ POA
LS-G133786-20UG
5 ug
£ POA
LS-G133786-5UG
Über dieses Produkt
- SKU:
- LS-G133786
- Zusätzliche Namen:
- GDF15, MIC1, MIC-1, NAG-1, NRG-1, NSAID-regulated gene 1 protein, PLAB, NSAID-activated gene 1 protein, Placental TGF-beta, PTGFB, GDF-15, PTGF-beta
- Buffer:
- Lyophilized with no additives
- Weitere Details:
- GDF-15 belongs to the TGF-B Beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Recombinant Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 112 amino acid polypeptide chains. The calculated molecular weight of Recombinant Human GDF-15/MIC-1 is 24.6 kDa.
- Molekulargewicht:
- 24.6 kDa
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >95%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- LifeSpan Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:133786