BRCA1 Antibody (aa762-1315)
Produktgrößen
100 ug
£ POA
LS-C83427-100UG
Über dieses Produkt
- SKU:
- LS-C83427
- Zusätzliche Namen:
- BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS
- Anwendung:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, pH 7.4
- Klonalität:
- Monoclonal
- Host:
- Mouse
- Immunogen:
- GST fusion protein expressed in E. coli corresponding to aa 762-1315 of full-length BRCA1.
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Spezifität:
- Recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the ~exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles., 2-8[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- LifeSpan Biosciences
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:84266