APG4B / ATG4B Antibody (FITC)
Produktgrößen
100 ug
£ POA
LS-C498411-100UG
50 ug
£ POA
LS-C498411-50UG
Über dieses Produkt
- SKU:
- LS-C498411
- Zusätzliche Namen:
- ATG4B, APG4 autophagy 4 homolog B, AUTL1, Autophagin-1, Cysteine protease ATG4B, HAPG4B, APG4B, KIAA0943
- Anwendung:
- ELISA
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cysteine protease ATG4B protein (350-400AA)
- Isotyp:
- IgG
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Spezifität:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.
- Lagerbedingungen:
- -70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- LifeSpan Biosciences
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:511925