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Antikörper

APP / Beta Amyloid Precursor Antibody (C-Terminus)

Produktgrößen
0.1 mg
£ POA
LS-C42820-0.1MG
Über dieses Produkt
SKU:
LS-C42820
Zusätzliche Namen:
APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II
Anwendung:
IHC-Paraffin, Western Blot
Buffer:
PBS, 0.02% Sodium Azide
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to amino acids 737-751 of human APP (C-TERMINAL).
Isotyp:
IgG
Aufreinigung:
Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Ambient
Spezifität:
Recognizes both intact Amyloid Precursor Protein (APP), and also the C99 fragment generated by Beta-secretase. The sequence recognized by this corresponds to amino acids 85-99 of the C99 fragment. The C99 fragment itself is a substrate for gamma-secretase to generate the 4 kD beta amyloid peptide, found in the brains of Alzheimer's disease patients. APP also inhibits Notch signaling through it's i
Lagerbedingungen:
2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
LifeSpan Biosciences
Typ:
Antibody: Polyclonal Antibody
  • Datenblatt des Herstellers:42558
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