UBE2S
Produktgrößen
0.8 nmol
£320,00
UB-0221-0008-0.8NMOL
Über dieses Produkt
- SKU:
- UB-0221-0008
- Anwendung:
- Cell-based/Functional Assay
- Weitere Details:
- UBE2S (also known as E2-24K or E2-EPF) is an E2 conjugating enzyme that is involved in the ubiquitylation of target substrates along with E1 and E3 enzymes. It has been implicated in the ubiquitylation of anaphase-promoting complex (APC/C), promoting the elongation of K11-linked polyubiquitin chains on this substrate, after initial ubiquitylation by either UBE2C or UBE2D1. This polyubiquitin chain elongation enhances the degradation of APC/C by the proteasome. UBE2S also targets von Hippel-Lindau (VHL) for proteasome degradation, resulting in the stabilization of HIF-1a.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
