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Proteine und Peptide

PTC-209

Produktgrößen
5 mg
£370,00
SI-9855-0005-5MG
Über dieses Produkt
SKU:
SI-9855-0005
Anwendung:
Cell-based/Functional Assay
CAS Number:
1217022-63-3
Weitere Details:
Treatment of cells with PTC-209 leads to the selective reduction in the levels of BMI-1 protein (Kreso, van Galen et al. 2014). BMI-1 is a component of the polycomb PRC complex and interacts directly with the E3 ligase RING1A and/or RING2. The PRC complex mediates monoubiquitylation of histone H2A on Lys-119 and is involved in chromatin remodeling and repression of gene expression.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C
Hersteller:
LifeSensors
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors