Thalidomide, conjugating enzyme inhibitor
Produktgrößen
200 mg
£358,00
SI-9820-0200-200MG
Über dieses Produkt
- SKU:
- SI-9820-0200
- Weitere Details:
- Thalidomide binds to the E3 ubiquitin ligase complex formed between cereblon (CRBN), damaged DNA binding protein 1 (DDB1), and Cul4A inhibiting ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Thalidomide initiates its teratogenic effects by binding to CRBN and inhibiting the associated ubiquitin E3 ligase activity. Cell permeable. Caution: Teratogenic.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
