MLN9708
Produktgrößen
5 mg
£518,00
SI-9715-0005-5MG
Über dieses Produkt
- SKU:
- SI-9715-0005
- Anwendung:
- Cell-based/Functional Assay
- CAS Number:
- 1201902-80-8
- Weitere Details:
- MLN9708 is a proteasome inhibitor. Much like Bortezomib, the active form of MLN9708 selectively and reversibly inhibits the chymotrypsin-like proteolytic (B Beta5) site of the 20S proteasome, with IC50 and Ki of 3.4 nM and 0.93 nM, respectively. MLN9708 is the prodrug form of MLN2238; the two compounds are also known as ixazomib citrate and ixazomib, respectively. Under physiological conditions, the boronic citrate ester is rapidly hydrolyzed to a boronic acid. Ixazomib has been used in combination therapy as a treatment for multiple myeloma, and studies indicate that it has the potential to treat other cancers as well.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors