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Proteine und Peptide

Spautin 1

Produktgrößen
5 mg
£265,00
SI-9644-0005-5MG
Über dieses Produkt
SKU:
SI-9644-0005
Anwendung:
Cell-based/Functional Assay
CAS Number:
126288-28-7
Weitere Details:
Spautin 1 inhibits USP10 and USP13 with IC50's of 0.6 uM and 0.7 uM, respectively. These deubiquitylases target the Beclin-1 subunit and promote degradation of Vps34-PI3 kinase complexes. Its effect on autophagy is Beclin-independent. Spautin induces apoptosis of cancer cells under starvation conditions.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C
Hersteller:
LifeSensors
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors