LDN-57444, DUB inhibitor
Produktgrößen
10 mg
£326,00
SI-9639-0010-10MG
Über dieses Produkt
- SKU:
- SI-9639-0010
- Anwendung:
- Cell-based/Functional Assay
- CAS Number:
- 668467-91-2
- Weitere Details:
- LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 uM) with approximately 28-fold greater selectivity over UCH-L3. Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
