Ubiquitin- Vinylmethyl ester
Produktgrößen
50 ug
£524,00
SI-0240-0050-50UG
Über dieses Produkt
- SKU:
- SI-0240-0050
- Anwendung:
- Cell-based/Functional Assay
- Weitere Details:
- Ub-VME is synthesized by the conjugation of 4-amino-but-2-enoic methyl ester to the C-terminus of UbiquitindeltaG76. Binding of ubiquitin by deubiquitylases (DUBs), for instance UCH's and most USPs, positions the reactive vinyl bond next to the sulfhydryl-group of the active site cysteine. Nucleophilic attack by the sulfhydryl on the vinyl bond produces a stable, covalent thioether bond between Ubiquitin and the deubiquitylase. Thus Ub-VME is a potent suicide inhibitor of DUBs.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -70[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins