VH298
Produktgrößen
10 mg
£396,00
PC-1003-0010-10MG
Über dieses Produkt
- SKU:
- PC-1003-0010
- Anwendung:
- Cell-based/Functional Assay
- CAS Number:
- 2097381-85-4
- Weitere Details:
- VH298 is a cell permeable high-affinity inhibitor of E3 ubiquitin ligase VHL (Kd = 80-90 nM). It blocks interaction between VHL and HIF-A Alpha downstream of HIF-A Alpha hydroxylation, initiating a hypoxic response. Results in time- and concentration-dependent accumulation of hydroxylated HIF-A Alpha, and upregulates mRNA and protein levels of HIF target genes.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- LifeSensors
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
