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Proteine und Peptide

OTULIN

Produktgrößen
25 ug
£384,00
DB-0206-0025-25UG
Über dieses Produkt
SKU:
DB-0206-0025
Anwendung:
Cell-based/Functional Assay
Weitere Details:
Otulin (Gumby) is a deubiquitinase exhibiting high specificity for linear ubiquitin chains (M1). Its specific interactions with the proximal ubiquitin leads to the activation of the catalytic triad. Otulin binds to HOIP (RNF31), a component of the linear chain synthesizing E3 ligase complex called LUBAC and regulates its activity thus affecting NFK KappaB-regulated pathways and proinflammatory responses.
Versandbedingungen:
Dry Ice
Lagerbedingungen:
-70[o]C
Hersteller:
LifeSensors
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes